2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P3616
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide 98%
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin.
    Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
  • HY-P3621
    Biotinyl-Glucagon (1-29), human, bovine, porcine 98%
    Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream.
    Biotinyl-Glucagon (1-29), human, bovine, porcine
  • HY-P3632
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) 75921-88-9 98%
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes.
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine)
  • HY-P3635
    Cockroach Myoactive Peptide II 93240-39-2 98%
    Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body.
    Cockroach Myoactive Peptide II
  • HY-P3641
    Kisspeptin 13 374675-18-0 98%
    Kisspeptin 13 inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. Kisspeptin 13 interacts with α2-adrenergic and 5-HT2 serotonin receptors, exhibits antidepressant efficacy. Kisspeptin 13 is an activator for GPR54 and GnRH receptor, which enhances memory and can be used in Alzheimer's disease research.
    Kisspeptin 13
  • HY-P3650
    Cholecystokinin (1-21) 101831-07-6 98%
    Cholecystokinin (1-21) (CCK-1-21) is a cholecystokinin (CCK) fragment. Cholecystokinin (1-21) stimulates lipolysis in human adipose tissue.
    Cholecystokinin (1-21)
  • HY-P3652
    Cholecystokinin-33 (swine) 67256-27-3 98%
    Cholecystokinin-33 (swine) is a cholecystokinin (CCK) fragment. Cholecystokinin-33 (swine) can reduce food intake and gallbladder contraction.
    Cholecystokinin-33 (swine)
  • HY-P3767
    Auriculin B 90052-57-6 98%
    Auriculin B (ANP (126-150) (Rat)) is a rat-derived atrial natriuretic peptide. Auriculin B has potent vasodilatory and diuretic properties.
    Auriculin B
  • HY-P3784
    FKKSFKL-NH2 137168-33-3 98%
    FKKSFKL-NH2 is a protein kinase C-selective peptide. FKKSFKL-NH2 can be used for the research of various biochemical.
    FKKSFKL-NH2
  • HY-P3787
    Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 157382-69-9 98%
    Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is the SH2 domain ligand. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal.
    Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2
  • HY-P3829
    Beacon (47-73) 681153-68-4 98%
    Beacon (47-73) is a C-terminal peptide fragment 47-73 of Beacon, and Beacon is a protein of 73 amino acid. Beacon (47-73) can be used for metabolic syndrome research.
    Beacon (47-73)
  • HY-P3830
    Beacon (30-73) 98%
    Beacon (30-73) is an ubiquitin-like protein, consisting of 44 amino acids.
    Beacon (30-73)
  • HY-P3837
    Xenopsin-Related Peptide 2 117442-29-2 98%
    Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as syntheticBradykinin (HY-P0206).
    Xenopsin-Related Peptide 2
  • HY-P3848
    Tyr0-Neurokinin A 116868-93-0 98%
    Tyr0-Neurokinin A is a neuropeptide belongs to tachykinin peptide family. Tyr0-Neurokinin A is an agonist of Tacr2. Tyr0-Neurokinin A can be used in the research of insulin resistance, obesity, diabetes.
    Tyr0-Neurokinin A
  • HY-P3855
    Endokinin D 566151-48-2 98%
    Endokinin D is a human tachykinin and consist of 14 amino acid residues.
    Endokinin D
  • HY-P3864
    Pancreastatin (37-52), human 133605-57-9 98%
    Pancreastatin (37-52), human is a pancreastatin fragment. Pancreastatin a CgA-derived peptide (CgA residues 250–301) with biological activity, inhibited the releasing of insulin by islet beta cells.
    Pancreastatin (37-52), human
  • HY-P3865
    Pancreastatin (33-49), porcine 106507-61-3 98%
    Pancreastatin (33-49), porcine is a pancreastatin fragment. Pancreastatin is a peptide isolated from porcine pancreas which has insulin-suppressive actions in vitro. Pancreastatin (33-49), porcine enhances the priming effect of glucose.
    Pancreastatin (33-49), porcine
  • HY-P3866
    [Asu1,6]-Oxytocin 14317-68-1 98%
    [Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes.
    [Asu1,6]-Oxytocin
  • HY-P3875
    [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2 176785-25-4 98%
    [Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect.
    [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
  • HY-P3893
    PSTAIR 126675-53-4 98%
    PSTAIR is a monoclonal antibody that recognizes the PSTAIR sequence in Cdc28, PSTAIR can be used as loading control.
    PSTAIR
Cat. No. Product Name / Synonyms Application Reactivity